Cell competition and its possible relation to cancer.
نویسندگان
چکیده
Cell competition can occur when cells of different genotypes share the same developing compartment, with one genotype displacing the other as a result of a proliferative advantage. Studies of cell competition in Drosophila have identified an active process of cell assassination and corpse engulfment, and also roles for Myc and the Warts/Hippo tumor suppressor pathway. Here, we discuss the possible relevance of cell competition to cancer.
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ورودعنوان ژورنال:
- Cancer research
دوره 68 14 شماره
صفحات -
تاریخ انتشار 2008